Drive Medical Innovations as a Computational Scientific Technician

Join the Shahmoradian Lab at the UT Southwestern Medical Center, affiliated with the renowned O'Donnell Brain Institute, and make a tangible impact on the future of healthcare. We are actively seeking a full-time Computational Scientific Technician with a strong preference for candidates who demonstrate experience or aptitude in Linux systems and programming. This specialized role focuses on the critically important field of cryo-electron microscopy computational analysis. We are a community that values diversity and inclusivity, and we're committed to pioneering research that aims to alleviate human suffering.


  • Cryo-Electron Microscopy Particle Picking for Therapeutics: Engage in daily particle picking activities crucial for cryo-electron microscopy. Utilize both manual and automated tools like Topaz auto-picking, adhering to rigorous, standard protocols.
  • Software Optimization for Structural Resolution: Gain proficiency in cutting-edge software tools to optimize the collection of high-resolution atomic structures, a foundation for developing future therapies for human diseases.
  • Linux Systems and Programming in Structural Biology: Utilize Linux-based systems to execute basic programming tasks and command line operations, key components of our computational analysis pipeline.
  • Data Analysis for Therapeutic Discovery: Conduct precise statistical analyses on cryo-electron microscopy data, directly contributing to the lab’s objectives of resolving atomic structures for future medical applications.
  • Protocols and Documentation: Maintain strict adherence to both written and verbal protocols, keeping detailed notes and records to ensure the scientific rigor and reproducibility of our groundbreaking research.


  • Strong Linux and programming aptitude
  • Punctual and reliable
  • High attention to detail
  • Proficient note-taking and record-keeping
  • Ability to rigorously follow and replicate protocols


  • High school / GED diploma
  • 1-2 professional work references
  • Strong preference for experience or aptitude in Linux systems and programming

By joining the Shahmoradian Lab, you will integrate into a team with a proven track record in high-resolution atomic structure determination. These structures are pivotal for the development of future therapies for human diseases. Your computational skills will be invaluable in advancing our research and will contribute directly to pioneering healthcare solutions.

Embark on a career where your computational expertise becomes an instrument for medical innovation. Align your skills with a purpose that extends beyond code and data—here, you have the opportunity to build the future of medicine. Join us in making a difference.

University Highlights:

  • Several employee benefits including free health insurance for full-time staff, and excellent coverage for dependents
  • Ranked No. 1 in the world among healthcare institutions in biomedical sciences (Nature Index 2019)
  • Highly collaborative and inclusive environment encompassing the entire spectrum of basic, translational, and clinical research

Living Environment:

The Dallas-Fort Worth Metroplex is home to:

  • Top educational school systems in Texas and the nation
  • Dallas Arts District, the largest contiguous urban arts district in the United States, covering contiguous ~120 acres (0.5 square kilometer)
  • “Deep Ellum”, the live music capital of North Texas and a hub for the performing arts from theater to comedy
  • Several parks and lakes great for boating and camping
  • Multitude of great dining and shopping options
  • Central location in the US, with easy access to major international airport and a smaller national airport

To apply, please fill out the form below. 

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